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Outdated rules on expenses prevent academics from travelling more sustainably Nature (IF 50.5) Pub Date : 2025-02-11
Letter to the Editor
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Amazing Australopithecus — excitement from 1925 about a ‘man ape’ fossil find Nature (IF 50.5) Pub Date : 2025-02-11
Snippets from Nature’s past.
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Close the biodiversity funding gap by teaching conservation to financial professionals Nature (IF 50.5) Pub Date : 2025-02-11
Letter to the Editor
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‘Aqua tweezers’ manipulate particles with water waves Nature (IF 50.5) Pub Date : 2025-02-11
Researchers create precise 3D patterns with water-waves.
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Nature markets are nothing new — they are widespread, regulated and instructive Nature (IF 50.5) Pub Date : 2025-02-11
Letter to the Editor
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Federico Mayor Zaragoza obituary: former UNESCO chief who championed neonatal screening Nature (IF 50.5) Pub Date : 2025-02-11
The biochemist introduced the first heel-prick tests for newborn babies in Spain, protecting infants from life-changing metabolic conditions.
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Your brain is full of microplastics: are they harming you? Nature (IF 50.5) Pub Date : 2025-02-11
Plastics have infiltrated every recess of the planet, including your lungs, kidneys and other sensitive organs. Scientists are scrambling to understand their effects on health.
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‘Male-dominated campuses belong to the past’: the University of Tokyo tackles the gender gap Nature (IF 50.5) Pub Date : 2025-02-11
A range of initiatives, from financial-support schemes to awareness campaigns, is already changing the university’s environment.
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Japan can be a science heavyweight once more — if it rethinks funding Nature (IF 50.5) Pub Date : 2025-02-11 Keisuke Goda, Tatsushi Igaki, Bernd Kuhn, Noboru Mizushima, Takeharu Nagai, Atsuhiro Nakagawa, Noriko Osumi, Amy Q. Shen, Masahiro Sonoshita, Masashi Yanagisawa
The nation must lose its tight focus on individual disciplines if it is to keep pace with the evolving requirements of scientific enquiry.
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Earth’s mysterious inner core really is changing shape Nature (IF 50.5) Pub Date : 2025-02-10
Earthquakes ringing through the planet illuminate how its heart is transforming.
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The Greenland Ice Sheet is fracturing faster than expected Nature (IF 50.5) Pub Date : 2025-02-10 Holly Smith
Cracks in Greenland's glaciers deepened by climate change.
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A man was destined for early Alzheimer’s — these genes might explain his escape Nature (IF 50.5) Pub Date : 2025-02-10
Scientists identify nine genetic variants that could have helped a man to avoid dementia for at least two decades longer than expected.
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Daily briefing: How did childhood evolve? Nature (IF 50.5) Pub Date : 2025-02-10
An AI system is crushing it at the International Mathematical Olympiad. Plus, what an iconic fossil teaches us about the evolution of childhood.
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‘Devastating’ cuts to NIH grants by Trump’s team put on hold by US judge Nature (IF 50.5) Pub Date : 2025-02-10
The ruling temporarily halts a policy slashing research overhead costs in 22 states, which filed a lawsuit against the biomedical agency.
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Author Correction: A map of the rubisco biochemical landscape Nature (IF 50.5) Pub Date : 2025-02-10 Noam Prywes, Naiya R. Phillips, Luke M. Oltrogge, Sebastian Lindner, Leah J. Taylor-Kearney, Yi-Chin Candace Tsai, Benoit de Pins, Aidan E. Cowan, Hana A. Chang, Renée Z. Wang, Laina N. Hall, Daniel Bellieny-Rabelo, Hunter M. Nisonoff, Rachel F. Weissman, Avi I. Flamholz, David Ding, Abhishek Y. Bhatt, Oliver Mueller-Cajar, Patrick M. Shih, Ron Milo, David F. Savage
Correction to: Nature https://doi.org/10.1038/s41586-024-08455-0 Published online 22 January 2025
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I grow medicinal mushrooms in my renewable-energy laboratory Nature (IF 50.5) Pub Date : 2025-02-10
When Ho Thi Thanh Van isn’t creating materials for fuel cells, she is cultivating traditional medicines.
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Breaking language barriers: ‘Not being fluent in English is often viewed as being an inferior scientist’ Nature (IF 50.5) Pub Date : 2025-02-10
Biologist Tatsuya Amano works to make science a fairer place for non-fluent speakers.
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How to end outrage and detoxify politics: share stories, not statistics Nature (IF 50.5) Pub Date : 2025-02-10
A book on human morality claims that although liberals and conservatives prioritize different victims, mutual understanding is still possible.
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How and why my company pivoted from energy to agritechnology Nature (IF 50.5) Pub Date : 2025-02-10
Lambda Agri chief executive Monica Saavedra describes funding strategies and the circumstances leading to the company changing strategic direction.
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Daily briefing: People in dense crowds move in swirls Nature (IF 50.5) Pub Date : 2025-02-07
People begin to move in vortices in densely packed crowds. Plus, the scientists who kept research alive in Gaza during the Israel–Hamas conflict.
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Daily briefing: How mantis shrimps survive landing the world’s fastest punch Nature (IF 50.5) Pub Date : 2025-02-07
What’s behind the mantis shrimp’s powerful punch? Plus, six ways to cultivate allyship for a diverse, equitable and inclusive academia.
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A novel sorption reactor for sorption heat transformers: Thermal energy storage system Energy Convers. Manag. (IF 9.9) Pub Date : 2025-02-10 Salman Hassanabadi, Ilya S. Girnik, Milad Ebadi, Majid Bahrami
This study addresses some of the critical limitations of current sorption heat transformer systems, particularly their cost, size and weight, which hinder their widespread adoption in various applications. A novel shell-and-tube sorption reactor design was proposed, featuring a lightweight shell instead of the conventional vacuum chambers typically used to encase the sorption reactor. In the proposed
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Numerical analysis and performance investigation of holographic spectrum-splitting concentrated photovoltaic-thermoelectric hybrid system with phase change material Energy Convers. Manag. (IF 9.9) Pub Date : 2025-02-10 Yue Hu, Piaopiao Li, Yucheng Yao, Hui Lv, Cheng Xu
To address the fluctuating nature of solar energy and achieve full spectrum utilization, a novel holographic spectrum-splitting concentration photovoltaic-thermoelectric hybrid system with phase change material is proposed in this study. Specifically, a two-layer volume holographic grating splitter is designed to separate the targeted spectrum from incident solar radiation for three spatially separated
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Giant RNA genomes: Roles of host, translation elongation, genome architecture, and proteome in nidoviruses Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Benjamin W. Neuman, Alexandria Smart, Orian Gilmer, Redmond P. Smyth, Josef Vaas, Nicolai B?ker, Dmitry V. Samborskiy, Ralf Bartenschlager, Stefan Seitz, Alexander E. Gorbalenya, Neva Caliskan, Chris Lauber
Positive-strand RNA viruses of the order Nidovirales have the largest known RNA genomes of vertebrate and invertebrate viruses with 36.7 and 41.1 kb, respectively. The acquisition of a proofreading exoribonuclease (ExoN) by an ancestral nidovirus enabled crossing of the 20 kb barrier. Other factors constraining genome size variations in nidoviruses remain poorly defined. We assemble 76 genome sequences
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Ancient origin and high diversity of zymocin-like killer toxins in the budding yeast subphylum Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Padraic G. Heneghan, Letal I. Salzberg, Eoin ? Cinnéide, Jan A. Dewald, Christina E. Weinberg, Kenneth H. Wolfe
Zymocin is a well-characterized killer toxin secreted by some strains of the yeast Kluyveromyces lactis . It acts by cleaving a specific tRNA in sensitive recipient cells. Zymocin is encoded by a killer plasmid or virus-like element (VLE), which is a linear DNA molecule located in the cytosol. We hypothesized that a tRNA-cleaving toxin similar to zymocin may have caused the three parallel changes to
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Clinical evaluation of patterned dried plasma spot cards to support quantification of HIV viral load and reflexive genotyping Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Giorgio Gianini Morbioli, Keith R. Baillargeon, Monalisa N. Kalimashe, Vibha Kana, Hloniphile Zwane, Cheri van der Walt, Allison J. Tierney, Andrea C. Mora, Mark Goosen, Rivashni Jagaroo, Jessica C. Brooks, Ewaldé Cutler, Gillian Hunt, Michael R. Jordan, Alice Tang, Charles R. Mace
Quantifying viral load, a key indicator required to achieve control and elimination of the HIV epidemic, requires cell-free plasma or serum to ensure measurements are not biased by proviral DNA contained in infected CD4 T lymphocytes. Plasma separation cards (PSC) collect and preserve a dried specimen, which makes them practical solutions for decentralized sample collection and transport in limited-resource
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Reenacting a mouse genetic evolutionary arms race in yeast reveals that SLXL1/SLX compete with SLY1/2 for binding to Spindlins Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Martin F. Arlt, Alyssa N. Kruger, Callie M. Swanepoel, Jacob L. Mueller
The house mouse X and Y chromosomes have recently acquired multicopy, rapidly evolving gene families representing an evolutionary arms race. This arms race between proteins encoded by X-linked Slxl1 / Slx and Y-linked Sly gene families can distort offspring sex ratio, but how these proteins compete remains unknown. Here, we report how Slxl1 / Slx and Sly encoded proteins compete in a protein family–specific
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Debiasing job ads by replacing masculine language increases gender diversity of applicant pools Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Joyce C. He, Sonia K. Kang
Job advertisements for jobs in male-dominated fields tend to contain more masculine language, and a commonly proposed intervention to increase gender diversity in applicant pools is to remove this language. In our research, we offer predictions about the broader impact of such interventions on individuals who may not “fit” with traditional masculine identity. Across four multimethod studies ( N = 37
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Inhibition of GABARAP or GABARAPL1 prevents aminoglycoside- induced hearing loss Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Jinan Li, Seung-Il Oh, Chang Liu, Bo Zhao
Aminoglycosides (AGs) are highly potent, broad-spectrum antibiotics frequently used as first-line treatments for multiple life-threatening infections. Despite their severe ototoxicity, causing irreversible hearing loss in millions of people annually, no preventive therapy has been approved. We previously reported that GABARAP and several other central autophagy proteins are essential for AG-induced
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Dynamic changes in histone lysine lactylation during meiosis prophase I in mouse spermatogenesis Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Xiaoyu Zhang, Yan Liu, Ning Wang
Male germ cells, which are responsible for producing millions of genetically diverse sperm through meiosis in the testis, rely on lactate as their central energy metabolite. Recent study has revealed that lactate induces epigenetic modification in cells through histone lysine lactylation. Here, we report dynamic histone lactylation at histone H4-lysine 5 (K5), -K8, and -K12 during meiosis prophase
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Seesaw protein: Design of a protein that adopts interconvertible alternative functional conformations and its dynamics Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Toma Ikeda, Tatsuya Nojima, Souma Yamamoto, Ryusei Yamada, Tatsuya Niwa, Hiroki Konno, Hideki Taguchi
According to classical Anfinsen’s dogma, a protein folds into a single unique conformation with minimal Gibbs energy under physiological conditions. However, certain proteins may fold into two or more conformations from single amino acid sequences. Here, we designed a protein that adopts interconvertible alternative functional conformations, termed “seesaw” protein (SSP). An SSP was engineered by fusing
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Resolving the dynamic correlated disorder in KTa 1? x Nb x O 3 Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Xing He, Mayanak K. Gupta, Douglas L. Abernathy, Garrett E. Granroth, Feng Ye, Barry L. Winn, Lynn Boatner, Olivier Delaire
Understanding the complex temporal and spatial correlations of ions in disordered perovskite oxides is critical to rationalize their functional properties. Here, we provide insights into the longstanding controversy regarding the off-centering of transition metal (TM) ions in the archetypal ferroelectric alloy KTa 1 ? x Nb x O 3 (KTN). By mapping the full energy ( E ) and wavevector ( Q ) dependence
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Ethylene response factor SlERF.D6 promotes ripening in part through transcription factors SlDEAR2 and SlTCP12 Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Yao Chen, Xin Wang, Vincent Colantonio, Zhuo Gao, Yangang Pei, Tara Fish, Jie Ye, Lance Courtney, Theodore W. Thannhauser, Zhibiao Ye, Yongsheng Liu, Zhangjun Fei, Mingchun Liu, James J. Giovannoni
Ripening is crucial for the development of fleshy fruits that release their seeds following consumption by frugivores and are important contributors to human health and nutritional security. Many genetic ripening regulators have been identified, especially in the model system tomato, yet more remain to be discovered and integrated into comprehensive regulatory models. Most tomato ripening genes have
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Machine learning–enhanced surface-enhanced spectroscopic detection of polycyclic aromatic hydrocarbons in the human placenta Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Oara Neumann, Yilong Ju, Andres B. Sanchez-Alvarado, Guodong Zhou, Weiwu Jiang, Bhagavatula Moorthy, Melissa A. Suter, Ankit Patel, Peter Nordlander, Naomi J. Halas
The detection and identification of polycyclic aromatic hydrocarbons (PAHs) and their derivatives, polycyclic aromatic compounds (PACs), are essential for environmental and health monitoring, for assessing toxicological exposure and their associated health risks. PAHs/PACs are the most dangerous chemicals found in tobacco smoke, and cigarette use during pregnancy can convey these molecules to the developing
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Wholesale flat subduction of the Indian slab and northward mantle convective flow: Plateau growth and driving force of the India–Asia collision Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Jincheng Ma, Xiaodong Song, Hans-Peter Bunge, Andreas Fichtner, You Tian
The tectonic evolution of the Tibetan Plateau has been influenced by continental collision and postcollisional convergence of Indian and Eurasian plates, both of which have undoubtedly imposed their imprints on the lithosphere and upper-mantle structures beneath the collision zone. However, the mode by which the Indian Plate has subducted beneath Tibet, and its driving forces, have been highly uncertain
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Early colonization of the deep-sea bottom—The protracted build-up of an ecosystem Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Luis A. Buatois, M. Gabriela Mángano, Maximiliano Paz, Nicholas J. Minter, Kai Zhou
Our understanding of the patterns and processes behind the evolution of deep-marine ecosystems is limited because the body-fossil record of the deep sea is poor. However, that gap in knowledge may be filled as deposits are host to diverse and abundant trace fossils that record the activities of benthic deep-marine organisms. Here, we built a global dataset of trace-fossil occurrences from a comprehensive
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Identification of FSH-regulated and estrous stage–specific transcriptional networks in mouse ovaries Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Kathryn Walters, Amber Baldwin, Zhenghui Liu, Mark Larsen, Neelanjan Mukherjee, T. Rajendra Kumar
Follicle-stimulating hormone (FSH) acts by binding to FSHRs expressed on ovarian granulosa cells and produces estradiol. FSH is essential for female fertility because mice lacking FSH ( Fshb KO ) are anestrous and infertile. Although several in vitro cell culture and ex vivo approaches combined with pharmacological hormone treatment were used to identify FSH-regulated genes, how FSH orchestrates ovarian
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Thermoelastic twisting–assisted crystal jumping based on a self-healing molecular crystal Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Zhihua Wang, Puxin Cheng, Wenqing Han, Rongchao Shi, Jian Xu, Yongshen Zheng, Jialiang Xu, Xian-He Bu
Adaptive crystals have attracted significant attention from solid-state chemists and crystal engineers for their promising applications in memories, capacitors, sensors, and actuators. Among them, thermosalient crystals are particularly favored thanks to their efficient energy conversions and rapid responses. However, the mechanisms for the mechanical responses of thermosalient crystals remain largely
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Bacterial species with different nanocolony morphologies have distinct flow-dependent colonization behaviors Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Kelsey M. Hallinen, Steven P. Bodine, Howard A. Stone, Tom W. Muir, Ned S. Wingreen, Zemer Gitai
Fluid flows are dominant features of many bacterial environments, and flow can often impact bacterial behaviors in unexpected ways. For example, the most common type of cardiovascular infection is heart valve colonization by gram-positive bacteria like Staphylococcus aureus and Enterococcus faecalis (endocarditis). This behavior is counterintuitive because heart valves experience high shear rates that
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Astrocytic EphA4 signaling is important for the elimination of excitatory synapses in Alzheimer’s disease Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Xin Yang, Ye Wang, Yi Qiao, Jingwen Lin, Jackie K. Y. Lau, Wing-Yu Fu, Amy K. Y. Fu, Nancy Y. Ip
Cell surface receptors, including erythropoietin-producing hepatocellular A4 (EphA4), are important in regulating hippocampal synapse loss, which is the key driver of memory decline in Alzheimer’s disease (AD). However, the cell-specific roles and mechanisms of EphA4 are unclear. Here, we show that EphA4 expression is elevated in hippocampal CA1 astrocytes in AD conditions. Specific knockout of astrocytic
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Double assurance in the induction of axial development by egg dorsal determinants in Xenopus embryos Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Yagmur Azbazdar, Edward M. De Robertis
We recently reported that microinjection of Xenopus nodal-related ( xnr ) mRNAs into β-catenin-depleted Xenopus embryos rescued a complete dorsal axis. Xnrs mediate the signal of the Nieuwkoop center that induces the Spemann–Mangold organizer in the overlying mesoderm, a process inhibited by the Nodal antagonist Cerberus-short (CerS). However, β-catenin also induces a second signaling center in the
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Maple samaras recover autorotation following raindrop collisions Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-02-10 Breanna M. Schaeffer, Tadd T. Truscott, Andrew K. Dickerson
Samaras are known for their elegant and robust autorotation, a resilience that persists in the adverse conditions imposed by high-speed raindrops. Like flying insects, samaras descending from tall trees are likely to be struck by raindrops in an intense storm. In this study, we detail the collision dynamics for impact regions across the samara body and the drop-shedding mechanisms that samaras exhibit
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Dynamics of a thin elastic coating Int. J. Eng. Sci. (IF 5.7) Pub Date : 2025-02-10 Nihal Ege, Bar?? Erba?, Julius Kaplunov, Hazel Yücel
Forced vibrations of a thin elastic coating are considered. A long wave, multimode approximation is derived from the original 3D setup. It is governed by a 2D equation with the coefficients depending on trigonometric functions of the frequency parameter. The related explicit dispersion relations appear to be of general interest as well. Although the developed asymptotic formulation is oriented to the
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“We are a target”: scientific society under pressure after Trump DEI crackdown Nature (IF 50.5) Pub Date : 2025-02-07
The American Society for Microbiology deleted terms such as equity from its website, sparking protests from members.
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Have Trump’s anti-DEI orders hit private funders? HHMI halts inclusive science programme Nature (IF 50.5) Pub Date : 2025-02-07
The Howard Hughes Medical Institute, a huge funder of biomedical research, has cut a $60-million initiative to boost diversity in science education.
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DeepMind AI crushes tough maths problems on par with top human solvers Nature (IF 50.5) Pub Date : 2025-02-07
The company’s AlphaGeometry2 reaches the level of gold-medal students in the International Mathematical Olympiad.
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Multi-Objective optimization and thermodynamic analysis of a supercritical CO2 Brayton cycle in a solar-powered multigeneration plant for net-zero emission goals Energy Convers. Manag. (IF 9.9) Pub Date : 2025-02-08 Veli Bak?rc?o?lu, Hossein B. Jond, Fatih Yilmaz
The development, design, examination, and optimization of carbon-free power generation models are essential to achieve a sustainable future with net-zero emissions. This study introduces a novel multigeneration system, uniquely combining a supercritical CO2 Brayton cycle and a transcritical CO2 Rankine cycle, supported by a solar parabolic trough collector. The system integrates a reverse osmosis desalination
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Desiccant wheel combined with dual separated or single integrated heat pump? A comparison on energy consumption Energy Convers. Manag. (IF 9.9) Pub Date : 2025-02-08 Hequn Liu, Yining Geng, Shaochen Tian, Yafeng Gao, Xing Su
Heat pump combined desiccant wheel systems have significant potential for industrial dehumidification. This study aims to define the usage boundaries between desiccant wheel systems combined with dual separated or single integrated heat pumps by selecting the most energy-efficient system configuration under various conditions. Two simulation models are developed to evaluate energy consumption under
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A comprehensive review of the evolution of biodiesel production technologies Energy Convers. Manag. (IF 9.9) Pub Date : 2025-02-08 Mehedi Hassan Pranta, Haeng Muk Cho
Biodiesel, compatible with compression ignition engines, is a promising alternative to fossil fuels due to its renewable and environmentally friendly nature. However, the high cost of biodiesel production stems from inefficiencies in industrial processes. This review summarizes the recent developments in advanced biodiesel synthesis techniques, evaluating various catalysts, including homogeneous, heterogeneous
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Design of lightweight hydraulic power unit for legged robots based on the Sobol sensitivity analysis Energy Convers. Manag. (IF 9.9) Pub Date : 2025-02-08 Bin Yu, Huashun Li, Chengze Gu, Ao Shen, Shuai Zhang, Xu Liu, Jingbin Li, Kaixian Ba, Guoliang Ma, Xiangdong Kong
Reducing the weight of the legged robot improves its endurance, maneuverability, and carrying capacity, enabling it to perform more complex tasks, such as transitioning from walking on flat terrain to executing challenging jumps. As the core energy source of a hydraulic legged robot, the weight of hydraulic power unit (HPU) accounts for more than 50% of the entire robot, offering significant potential
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Eco-friendly hydrogen and power co-production system with a flexible operational strategy Energy Convers. Manag. (IF 9.9) Pub Date : 2025-02-08 Taehyun Kim, Yungeon Kim, Jinwoo Park
Reducing the cost of clean hydrogen production is essential to combat global warming and advance the hydrogen economy. Integrating water electrolysis with complementary systems offers a promising approach to developing a hybrid hydrogen production framework. Therefore, this study aims to propose a hydrogen and power co-production system with a flexible operational strategy to reduce hydrogen production
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Well-to-Pump life cycle Assessment of methanol derived from high ash Coal, natural Gas, and municipal solid waste Energy Convers. Manag. (IF 9.9) Pub Date : 2025-02-08 Srijit Biswas, Arpit Yadav, Avinash Kumar Agarwal
With growing energy needs and the increasing threat of climate change, it becomes necessary to study the impact and feasibility of alternative fuels compared to conventional fossil fuels. One such alternative fuel is Methanol, which is also used widely in the chemical and pharmaceutical industries. It can be blended with gasoline/ diesel or used as 100% Methanol. Conventionally, Methanol is produced
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Poetry on Mars and robots on Earth: Books in brief Nature (IF 50.5) Pub Date : 2025-02-07
Andrew Robinson reviews five of the best science picks.
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Bonobos know when you’re in the know ― and when you’re not Nature (IF 50.5) Pub Date : 2025-02-07
The apes can tailor their communications to account for a human partner’s level of knowledge.
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From viral variants to devastating storms, how names shape the public's reaction to science Nature (IF 50.5) Pub Date : 2025-02-07
In episode 2 of 'What's in a name' we look at the how names can help scientists communicate with the public.
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Scientists globally are racing to save vital health databases taken down amid Trump chaos Nature (IF 50.5) Pub Date : 2025-02-07
The mass-archiving effort is in response to the US Centers for Disease Control and Prevention removing some of its web pages.
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How my research focus exposed me to threats and harassment Nature (IF 50.5) Pub Date : 2025-02-07
Researchers who investigate highly-politicized topics can face harassment, others for their race, gender identity or disability. Two scientists share their stories.
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Granzyme K activates the entire complement cascade Nature (IF 50.5) Pub Date : 2025-02-06 Carlos A. Donado, Erin Theisen, Fan Zhang, Aparna Nathan, Madison L. Fairfield, Karishma Vijay Rupani, Dominique Jones, Kellsey P. Johannes, Soumya Raychaudhuri, Daniel F. Dwyer, A. Helena Jonsson, Michael B. Brenner
Granzymes are a family of serine proteases mainly expressed by CD8+ T cells, natural killer cells, and innate-like lymphocytes1. Although their primary function is thought to be the induction of cell death in virally infected and tumor cells, accumulating evidence indicates certain granzymes can elicit inflammation by acting on extracellular substrates1. Recently, we found that the majority of tissue
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Mantis shrimp have the world’s fastest punch — here’s how their limbs survive Nature (IF 50.5) Pub Date : 2025-02-06
Insights from probing the shock-absorbing layer within the crustacean’s club-like claw could inspire the design of tough new materials.